Standard Svensk standard · SS-EN ISO 21427-2:2009/AC:2013

Vattenundersökningar - Bestämning av genotoxicitet genom bildning av mikrokärnor - Del 2: Metod med V79-celler från kinesisk hamster (ISO 21427-2:2006/Cor 1:2009)

Status: Gällande

Omfattning
This part of ISO 21427 specifies a method for the determination of genotoxicity of water and waste water using a mammalian in vitro test which detects damage, induced by water-soluble substances, to the chromosomes or the mitotic apparatus of V79 cells from the Chinese hamster. The micronucleus test allows the identification of substances that cause cytogenetic damage which results in the formation of micronuclei containing lagging chromosome fragments and/or whole chromosomes. The assay is based on the increase in the frequency of micronucleated cells after incubation with and without metabolic activation.

Ämnesområden

Undersökning av vattens biologiska egenskaper (13.060.70)


Produktinformation

Språk: Engelska

Framtagen av: Biologiska vattenundersökningar, SIS/TK 426

Internationell titel: Water quality - Evaluation of genotoxicity by measurement of the induction of micronuclei - Part 2: Mixed population method using the cell line V79 (ISO 21427-2:2006/Cor 1:2009)

Artikelnummer: STD-98842

Utgåva: 1

Fastställd: 2013-08-21

Antal sidor: 8

Korrigerar: SS-EN ISO 21427-2:2009