This International Standard specifies the dimensions of agent-specific filling systems for agent-specific anaesthetic vaporizers. This International Standard does not specify construction materials. Materials used for the parts of filling systems which come into contact with liquid anaesthetic agent should be selected with regard to: a) toxicity; b) compatibility with anaesthetic agents; c) minimization of health risks due to substances leached from the materials. Because of the unique properties of desflurane, dimensions for this agent have not been specified in this International Standard. NOTE Designs of connection systems are encouraged which only permit engagement of the agent-specific bottle adaptor to the bottle when the bottle collar is in place.